Gene description for Anapc5
Gene name anaphase-promoting complex subunit 5
Gene symbol Anapc5
Other names/aliases 2510006G12Rik
AA408751
AA536819
AA986414
APC5
Anpc5
Species Mus musculus
 Database cross references - Anapc5
ExoCarta ExoCarta_59008
Entrez Gene 59008
UniProt Q8BTZ4  
 Anapc5 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Anapc5
Molecular Function
    protein phosphatase binding GO:0019903 ISO
Biological Process
    cell cycle GO:0007049 IEA
    cell division GO:0051301 IEA
    mitotic nuclear division GO:0007067 IEA
    protein K11-linked ubiquitination GO:0070979 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    anaphase-promoting complex GO:0005680 ISO
 Experiment description of studies that identified Anapc5 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Anapc5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMURF2  
Affinity Capture-Luminescence Homo sapiens
2 TGFBR1  
Affinity Capture-Luminescence Homo sapiens
3 SMURF1 57154
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml



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