Gene description for FBN1
Gene name	fibrillin 1
Gene symbol	FBN1
Other names/aliases	ACMICD ECTOL1 FBN GPHYSD2 MASS MFS1 OCTD SGS SSKS WMS WMS2
Species	Homo sapiens
Database cross references - FBN1
ExoCarta	ExoCarta_2200
Entrez Gene	2200
HGNC	3603
MIM	134797
UniProt	P35555
FBN1 identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for FBN1

Molecular Function     protein complex binding GO:0032403 IPI     protein binding GO:0005515 IPI     extracellular matrix structural constituent GO:0005201 IDA     integrin binding GO:0005178 IPI     calcium ion binding GO:0005509 IDA Biological Process     sequestering of TGFbeta in extracellular matrix GO:0035583 ISS     heart development GO:0007507 IMP     anatomical structure morphogenesis GO:0009653 IBA     metanephros development GO:0001656 IEA     extracellular matrix disassembly GO:0022617 TAS     cellular response to transforming growth factor beta stimulus GO:0071560 IEA     skeletal system development GO:0001501 IMP     sequestering of BMP in extracellular matrix GO:0035582 ISS     regulation of cellular response to growth factor stimulus GO:0090287 IBA     extracellular matrix organization GO:0030198 TAS Subcellular Localization     basement membrane GO:0005604 IDA     extracellular matrix GO:0031012 IDA     extracellular exosome GO:0070062 IDA     extracellular space GO:0005615 IDA     extracellular region GO:0005576 TAS     proteinaceous extracellular matrix GO:0005578 IDA     microfibril GO:0001527 IDA