Gene description for PHKB
Gene name phosphorylase kinase, beta
Gene symbol PHKB
Other names/aliases -
Species Homo sapiens
 Database cross references - PHKB
ExoCarta ExoCarta_5257
Entrez Gene 5257
HGNC 8927
MIM 172490
UniProt Q93100  
 PHKB identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PHKB
Molecular Function
    calmodulin binding GO:0005516 IEA
    phosphorylase kinase activity GO:0004689 IBA
    protein binding GO:0005515 IPI
Biological Process
    carbohydrate metabolic process GO:0005975 TAS
    small molecule metabolic process GO:0044281 TAS
    glycogen metabolic process GO:0005977 TAS
    glycogen catabolic process GO:0005980 TAS
    protein phosphorylation GO:0006468 IBA
    generation of precursor metabolites and energy GO:0006091 TAS
    glucose metabolic process GO:0006006 TAS
Subcellular Localization
    cytosol GO:0005829 TAS
    phosphorylase kinase complex GO:0005964 IBA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified PHKB in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PHKB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPC 3183
Two-hybrid Homo sapiens
2 C20orf27 54976
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which PHKB is involved
Glycogen breakdown (glycogenolysis) TAS Reactome

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