Gene description for WSB2
Gene name WD repeat and SOCS box containing 2
Gene symbol WSB2
Other names/aliases SBA2
Species Homo sapiens
 Database cross references - WSB2
ExoCarta ExoCarta_55884
Entrez Gene 55884
HGNC 19222
UniProt Q9NYS7  
 WSB2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for WSB2
Biological Process
    protein ubiquitination GO:0016567 IEA
    intracellular signal transduction GO:0035556 IEA
Subcellular Localization
    intracellular GO:0005622 IEA
 Experiment description of studies that identified WSB2 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for WSB2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EZH2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which WSB2 is involved
No pathways found





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