Gene description for LDHAL6B
Gene name lactate dehydrogenase A-like 6B
Gene symbol LDHAL6B
Other names/aliases LDH6B
LDHAL6
LDHL
Species Homo sapiens
 Database cross references - LDHAL6B
ExoCarta ExoCarta_92483
Entrez Gene 92483
HGNC 21481
UniProt Q9BYZ2  
 LDHAL6B identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
Squamous carcinoma cells 20124223    
 Gene ontology annotations for LDHAL6B
Molecular Function
    L-lactate dehydrogenase activity GO:0004459 IEA
    protein binding GO:0005515 IPI
Biological Process
    carboxylic acid metabolic process GO:0019752 IEA
    carbohydrate metabolic process GO:0005975 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified LDHAL6B in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
2
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LDHAL6B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LDHAL6B is involved
No pathways found





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