Experiment description of studies that identified MS4A1 in sEVs

1 Experiment ID 79 MISEV standards ✘ Biophysical techniques ✔ CD81|MHCII Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20458337     Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W." Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting

2 Experiment ID 80 MISEV standards ✘ Biophysical techniques ✔ CD81|MHCII Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20458337     Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W." Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting

3 Experiment ID 81 MISEV standards ✘ Biophysical techniques ✔ CD81|MHCII Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20458337     Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W." Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting

4 Experiment ID 217 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|CD81|CD9|CD63 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O." Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for MS4A1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YWHAH 7533 Affinity Capture-MS Homo sapiens 2 ATG16L1 55054 Affinity Capture-MS Homo sapiens 3 CD40 958 Affinity Capture-Western Homo sapiens 4 FMNL1 752 Affinity Capture-MS Homo sapiens 5 SLC10A6   Two-hybrid Homo sapiens 6 RNF19B   Two-hybrid Homo sapiens 7 YWHAB 7529 Affinity Capture-MS Homo sapiens 8 HLA-DRA 3122 Affinity Capture-MS Homo sapiens Co-localization Homo sapiens 9 THAP4 51078 Two-hybrid Homo sapiens 10 MTIF3   Two-hybrid Homo sapiens 11 SLC10A1   Two-hybrid Homo sapiens 12 FCRL3   Two-hybrid Homo sapiens 13 HSD17B11 51170 Two-hybrid Homo sapiens 14 LCK 3932 Affinity Capture-Western Homo sapiens 15 PRDM1   Co-localization Homo sapiens 16 YWHAZ 7534 Affinity Capture-MS Homo sapiens 17 HLA-DRB4   Affinity Capture-MS Homo sapiens 18 REEP4   Two-hybrid Homo sapiens 19 CCDC155   Two-hybrid Homo sapiens 20 REEP2   Two-hybrid Homo sapiens 21 TMEM72   Two-hybrid Homo sapiens 22 TMEM82   Two-hybrid Homo sapiens 23 CREB3L1   Two-hybrid Homo sapiens 24 RNF5   Two-hybrid Homo sapiens 25 LEUTX   Two-hybrid Homo sapiens 26 GORAB 92344 Two-hybrid Homo sapiens 27 FAM209A 200232 Two-hybrid Homo sapiens 28 GPR42   Two-hybrid Homo sapiens 29 IL7R   Two-hybrid Homo sapiens 30 HSD17B13   Two-hybrid Homo sapiens 31 HLA-DRB3 3125 Affinity Capture-MS Homo sapiens 32 MMD   Two-hybrid Homo sapiens 33 ACKR2   Two-hybrid Homo sapiens 34 TMPPE   Two-hybrid Homo sapiens 35 HLA-DRB5 3127 Affinity Capture-MS Homo sapiens 36 FBXW7   Synthetic Lethality Homo sapiens 37 CREB3   Two-hybrid Homo sapiens 38 YWHAQ 10971 Affinity Capture-MS Homo sapiens 39 FYN 2534 Affinity Capture-Western Homo sapiens 40 TMEM31   Two-hybrid Homo sapiens 41 YWHAG 7532 Affinity Capture-MS Homo sapiens 42 YWHAE 7531 Affinity Capture-MS Homo sapiens 43 HLA-DRB1 3123 Affinity Capture-MS Homo sapiens 44 CLEC14A   Two-hybrid Homo sapiens 45 TSPO2   Two-hybrid Homo sapiens 46 HIATL1 84641 Two-hybrid Homo sapiens 47 TMX2 51075 Two-hybrid Homo sapiens View the network

Pathways in which MS4A1 is involved

No pathways found