Gene description for MORC3
Gene name MORC family CW-type zinc finger 3
Gene symbol MORC3
Other names/aliases NXP2
ZCW5
ZCWCC3
Species Homo sapiens
 Database cross references - MORC3
ExoCarta ExoCarta_23515
Entrez Gene 23515
HGNC 23572
MIM 610078
UniProt Q14149  
 MORC3 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for MORC3
Molecular Function
    zinc ion binding GO:0008270 IEA
Biological Process
    post-embryonic development GO:0009791 IEA
    protein stabilization GO:0050821 IDA
    cell aging GO:0007569 IDA
    peptidyl-serine phosphorylation GO:0018105 IDA
    negative regulation of fibroblast proliferation GO:0048147 IDA
    protein phosphorylation GO:0006468 IDA
    maintenance of protein location in nucleus GO:0051457 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    PML body GO:0016605 IDA
    intermediate filament cytoskeleton GO:0045111 IDA
 Experiment description of studies that identified MORC3 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MORC3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MORC3 is involved
No pathways found





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