Gene description for NAT14
Gene name N-acetyltransferase 14 (GCN5-related, putative)
Gene symbol NAT14
Other names/aliases KLP1
Species Homo sapiens
 Database cross references - NAT14
ExoCarta ExoCarta_57106
Vesiclepedia VP_57106
Entrez Gene 57106
HGNC 28918
UniProt Q8WUY8  
 NAT14 identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for NAT14
Molecular Function
    DNA binding GO:0003677 IEA
    N-acetyltransferase activity GO:0008080 IBA
Biological Process
    DNA-templated transcription initiation GO:0006352 NAS
    positive regulation of DNA-templated transcription GO:0045893 NAS
Subcellular Localization
    nucleus GO:0005634 NAS
    membrane GO:0016020 IEA
 Experiment description of studies that identified NAT14 in exosomes
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for NAT14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC39A12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 RAMP3  
Affinity Capture-MS Homo sapiens
3 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
4 TSPAN5 10098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 C4orf32  
Affinity Capture-MS Homo sapiens
6 VNN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 YAE1D1  
Two-hybrid Homo sapiens
8 F2RL1  
Two-hybrid Homo sapiens
9 TTYH1  
Affinity Capture-MS Homo sapiens
10 SIDT2 51092
Affinity Capture-MS Homo sapiens
11 C3AR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 SCPEP1 59342
Affinity Capture-MS Homo sapiens
13 PEX19 5824
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 STK32C  
Affinity Capture-MS Homo sapiens
15 CCR4 1233
Two-hybrid Homo sapiens
16 ADRB2  
Two-hybrid Homo sapiens
17 KCNC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CMKLR1 1240
Affinity Capture-MS Homo sapiens
19 SCN4A  
Affinity Capture-MS Homo sapiens
20 TSPAN15 23555
Affinity Capture-MS Homo sapiens
21 CPQ 10404
Affinity Capture-MS Homo sapiens
22 AQP3  
Affinity Capture-MS Homo sapiens
23 SAAL1 113174
Affinity Capture-MS Homo sapiens
24 PPP4R1L  
Affinity Capture-MS Homo sapiens
25 TNFSF18 8995
Affinity Capture-MS Homo sapiens
26 TTC30B  
Affinity Capture-MS Homo sapiens
27 TMEM169  
Affinity Capture-MS Homo sapiens
28 HEPACAM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 JUN 3725
Two-hybrid Homo sapiens
30 CPVL 54504
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 SLC6A20  
Affinity Capture-MS Homo sapiens
32 MINPP1 9562
Affinity Capture-MS Homo sapiens
33 RABAC1 10567
Two-hybrid Homo sapiens
34 RPA3 6119
Proximity Label-MS Homo sapiens
35 KCNA10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 POMK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 SLC39A5 283375
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 TTC12  
Affinity Capture-MS Homo sapiens
39 DHRS4 10901
Affinity Capture-MS Homo sapiens
40 SLC24A3  
Affinity Capture-MS Homo sapiens
41 HTR2B  
Two-hybrid Homo sapiens
42 TRDN 10345
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 PTH2R  
Affinity Capture-MS Homo sapiens
44 SLC6A5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 KCNA2  
Affinity Capture-MS Homo sapiens
46 P2RY10  
Affinity Capture-MS Homo sapiens
47 INTS12  
Affinity Capture-MS Homo sapiens
48 UPK1A 11045
Affinity Capture-MS Homo sapiens
49 ZWILCH 55055
Affinity Capture-MS Homo sapiens
50 FUCA2 2519
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 CHRNA4  
Affinity Capture-MS Homo sapiens
52 CCDC47 57003
Affinity Capture-MS Homo sapiens
53 SLC7A1 6541
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 INTS4P2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 ATP2A1 487
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NAT14 is involved
No pathways found





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